A study into the effects of GOT on myasthenia Gravis.

Item

Title
A study into the effects of GOT on myasthenia Gravis.
Author(s)
Gillender, R
Abstract
Background- MG is an autoimmune disease affecting the acetylecholine receptors in muscles, most commonly in the face and the eyes MG is mainly treated with immunosuppressive drugs such as prednisolone, intravenous (IV) immunoglobulin therapy and plasmapheresis There are very few studies on the effects of any kind of physical therapy on MG. A study into the effects of balance strategy training (BST) and MG showed improved balance and proprioception for the participants GOT could mimic the effects of the BST. Objective- To investigate the effect of GOT on the symptoms of MG and the participants balance and proprioception. Design- A single case study using an ABAB design. Methods- Participants with MG had an initial case history taken and were then monitored for the pre-intervention phase of the experiment. Data was gathered from two questionnaires and balance board readings throughout the initial 2 weeks. They were then given 1 treatment a week for 2 weeks that consisted of a supine GOT routine done by a student osteopath under guidance from a fully qualified osteopath. This was then followed by a 2-week withdrawal phase where questionnaire data and balance board data were collected. The study finished on another 2-week treatment phase. Analysis was done using a statistical process control and Chi2 testing on questionnaire data. Results-Statistically significant results were shown on 2 of the 4 graphs for the balance board data showing an improvement in balance from treatment. Two out of the eight Chi-Squared tests (p=0.05) done on the questionnaire data rejected the null hypothesis however the others did not reject the null hypothesis. This suggests that GOT does have a positive effect on participants with MG but the extent is not yet clear. Discussion- Results from the current study were mixed and overall didn't reject the null hypothesis. However, there is evidence that GOT has a positive effect on the balance of the participants but it is not clear about the effect on the symptoms of MG and the participants QOL. Conclusion- Although some positive results were found, a longer study with more participants should be done in order to validate the use of osteopathic treatment for MG. A new research area has been opened up for osteopath and MG.
Date Accepted
2016
Date Submitted
2.12.2016 17:29:04
Type
osteo_thesis
Language
English
Submitted by:
62
Pub-Identifier
15946
Inst-Identifier
1229
Keywords
Myasthenia gravis, Osteopathic treatment, Balance board.
Recommended
0
Item sets
Thesis

Gillender, R, “A study into the effects of GOT on myasthenia Gravis.”, Osteopathic Research Web, accessed May 2, 2024, https://www.osteopathic-research.com/s/orw/item/535